Thermo Fisher Scientific JIP1 Polyclonal Antibody
Human JIP1 단백질을 인식하는 Goat 폴리클로날 항체로 Western blot에 적합합니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, TBS 버퍼(pH 7.3, 0.5% BSA)와 sodium azide를 포함합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence DSQEAKGNKCSH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933952 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:2,000.
Target Information
The protein encoded by this gene regulates pancreatic beta-cell function and is highly similar to JIP-1, a mouse protein known to regulate c-Jun amino-terminal kinase (MAPK8). It prevents MAPK8-mediated activation of transcription factors and reduces IL-1β and MEKK1-induced apoptosis in pancreatic beta cells. Additionally, it acts as a DNA-binding transactivator of the glucose transporter GLUT2. REST represses expression of this gene in insulin-secreting beta cells. Mutations in this gene are associated with type 2 diabetes susceptibility.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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