Thermo Fisher Scientific GSTA3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.1–0.3 µg/mL

Product Specifications

Product Specific Information

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Target Information

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes participate in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds.

Eight distinct classes of soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
This gene encodes a glutathione S-transferase belonging to the alpha class, located in a cluster on chromosome 6.
Alpha class genes encode enzymes with glutathione peroxidase activity, though evolutionary divergence has led to substrate specificity and catalytic differences.
The enzyme catalyzes the double bond isomerization of precursors for progesterone and testosterone during steroid hormone biosynthesis.
An additional transcript variant has been identified, but its full-length sequence has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.