Thermo Fisher Scientific CD9 Monoclonal Antibody (eBioSN4 (SN4 C3-3A2)), eBioscience
인간 CD9 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry, Immunoprecipitation, IHC(F) 등에 사용 가능. 0.5 mg/mL 농도의 액상 제품이며, PBS(pH 7.2) 버퍼와 0.09% sodium azide 함유. 4°C 보관, SDS-PAGE 기준 90% 이상 순도.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 2 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent | - |
| Flow Cytometry (Flow) | 0.5 µg/test | View 8 publications |
| Immunoprecipitation (IP) | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | eBioSN4 (SN4 C3-3A2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2864820 |
Additional Available Formats
- APC (Cat. 17-0098-42)
- Biotin (Cat. 13-0098-82)
- FITC (Cat. 11-0098-42)
- PE (Cat. 12-0098-42)
- PerCP-eFluor 710 (Cat. 46-0098-42)
- Super Bright 436 (Cat. 62-0098-42)
- Super Bright 645 (Cat. 64-0098-42)
- Request custom conjugation
Product Specific Information
Description:
The eBioSN4 monoclonal antibody reacts with human CD9, a 24 kDa tetraspanin family member characterized by four hydrophobic transmembrane domains. CD9 is expressed in platelets, eosinophils, basophils, pre-B cells, activated T cells, and neural cell lines. CD9 expression has been associated with malignant phenotypes, including high expression in non-T cell acute lymphoblastic leukemia and chronic lymphocytic leukemia. It plays roles in platelet aggregation, pre-B cell adhesion and migration, and T cell co-stimulation independently of CD28. The eBioSN4 antibody partially cross-blocks binding of another anti-human CD9 antibody, MM2/57.
Applications Reported:
Flow cytometric analysis, immunoprecipitation, and immunohistology of frozen tissue sections.
Applications Tested:
Tested by flow cytometric analysis of normal human platelets. Recommended ≤0.5 µg/test (100 µL final volume, 10⁵–10⁸ cells/test). Optimize titration for best performance.
Purity: >90% (SDS-PAGE)
Aggregation: <10% (HPLC)
Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD9 antigen is a glycoprotein expressed on developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, neurons, and glial cells. It belongs to the tetraspanin family, spanning the membrane four times. CD9 regulates activation and aggregation in pre-B cells and platelets, possibly via integrin CD41/CD61 (GPIIb/GPIIIa). It is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion. CD9 plays critical roles in cell adhesion, proliferation, and suppression of cancer cell motility and metastasis, acting as a metastasis suppressor in solid tumors.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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