Thermo Fisher Scientific Phospho-Nkx2.1 (Ser327) Polyclonal Antibody
Phospho-Nkx2.1 (Ser327) 인산화 부위를 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응. Western blot에 최적화(1:500–1:2,000 희석). TTF1의 Ser327 인산화 상태를 특이적으로 검출. 연구용으로만 사용 가능.
- 카탈로그번호
- PA5105174
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NKX2-1 (Accession P43699), corresponding to amino acid residues around phosphorylated Ser327 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816647 |
Product Specific Information
Antibody detects endogenous levels of TTF1 only when phosphorylated at Ser327.
Target Information
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but also regulates genes involved in morphogenesis.
Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer.
Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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