Thermo Fisher Scientific RAB40B Monoclonal Antibody (1A1)

Applications

Tested Dilution

Publications

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

1A1

Immunogen

RAB40B (AAH18039, 179 a.a. approximately 278 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RAB40B,uniProtId:Q12829-1,ncbiNodeId:9606,antigenRange:179-278,antigenLength:278,antigenImageFileName:H00010966-M01A_RAB40B_Q12829-1_House_mouse.svg,antigenImageFileNamePDP:H00010966-M01A_RAB40B_Q12829-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: GMDRLWRPSK VLSLQDLCCR AVVSCTPVHL VDKLPLPIAL RSHLKSFSMA NGLNARMMHG GSYSLTTSST HKRSSLRKVK LVRPPQSPPK NCTRNSCKIS

Target Information

Rab 40B is a 278 amino acid protein that belongs to the small GTPase superfamily and the Rab family. Rab 40B contains a SOCS box domain that mediates interactions with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes. Rab 40B shares similarity with a yeast protein, suggesting a role in regulation of secretory vesicles. The Rab 40B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 17q25.3. It has been suggested that there is a major gene locus on chromosome 17q25.3 for autosomal dominant moyamoya disease (MMD), which is an idiopathic steno-occlusive cerebrovascular disease that represents an important cause of stroke.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.