Thermo Fisher Scientific NMDAR1 Monoclonal Antibody (N308/48), APC
NMDAR1 단백질을 인식하는 마우스 단클론 항체로 APC 형광 표지. 인간, 생쥐, 랫트 시료에 반응하며 WB, IHC, ICC/IF에 사용 가능. 단백질 G로 정제된 액상 형태, 4°C 보관. 학습 및 기억 관련 시냅스 가소성 연구에 적합.
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Thermo Fisher Scientific NMDAR1 Monoclonal Antibody (N308/48), APC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N308/48 |
| Immunogen | Fusion protein amino acids 42–361 (extracellular N-terminus) of rat NR1 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932016 |
Additional Formats
- FITC (MA5-45563)
- PerCP (MA5-45564)
- Request custom conjugation
Product Specific Information
1 µg/mL of MA5-45562 was sufficient for detection of NR1 glutamate receptor in 20 µg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Detects approximately 105 kDa.
This antibody was formerly sold as clone S308-48.
Target Information
NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors (NMDA receptors), members of the glutamate receptor channel superfamily. These heteromeric protein complexes form ligand-gated ion channels that play a key role in synaptic plasticity, underlying memory and learning. Expression of different isoforms may contribute to functional diversity. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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