Thermo Fisher Scientific SUR1 Monoclonal Antibody (N289/16), PE
SUR1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, PE 형광 표지된 제품입니다. Western blot, IHC, ICC/IF에 사용 가능하며, 다양한 종(햄스터, 인간, 마우스, 랫트)에 반응합니다. 단백질 G 정제, 4°C 보관, 보존제 무첨가.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Hamster, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N289/16 |
| Immunogen | Fusion protein amino acids 1548–1582 (cytoplasmic C-terminus) of rat SUR1 |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932015 |
Available Formats
- Unconjugated (MA5-27660)
- APC (MA5-45558)
- FITC (MA5-45559)
- PerCP (MA5-45560)
- Request custom conjugation available
Product Specific Information
- 1 µg/mL of MA5-45561 detects SUR1 in 20 µg of mouse brain membrane lysate by colorimetric immunoblot using goat anti-mouse IgG:HRP as secondary antibody.
- Detects approximately 160 kDa.
- Does not cross-react with SUR2B.
- Formerly sold as clone S289-16.
Target Information
The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes and are divided into seven subfamilies. This protein belongs to the MRP subfamily, involved in multi-drug resistance. It modulates ATP-sensitive potassium channels and insulin release.
Mutations or deficiencies are associated with hyperinsulinemic hypoglycemia of infancy and non-insulin-dependent diabetes mellitus type II. Alternative splicing has been observed, but transcript variants are not fully characterized.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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