Thermo Fisher Scientific Phospho-JNK1/JNK2/JNK3 (Tyr185) Polyclonal Antibody
인간, 마우스, 랫트에서 반응하는 Rabbit Polyclonal 항체로, Tyr185에서 인산화된 JNK1/JNK2/JNK3를 검출합니다. Western blot에 적합하며, 고순도(>95%) 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태, 1 mg/mL 농도, 장기보관 시 -20°C에서 보관.
- 판매단위
- pk
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Thermo Fisher Scientific Phospho-JNK1/JNK2/JNK3 (Tyr185) Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Tyrosine 185 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553766 |
Product Specific Information
- Detects endogenous protein at molecular weights of 46 and 54 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases.
MAPKs are serine-threonine protein kinases activated by various extracellular stimuli and mediate signal transduction from the cell surface to the nucleus.
JNK is involved in cellular processes such as proliferation, differentiation, transcription regulation, and development.
JNK pathways are activated by stress and inflammatory signals.
JNK is expressed as ten different isoforms due to differential mRNA splicing, with JNK1 and JNK2 being predominant.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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