Thermo Fisher Scientific Phospho-GluR1 (Ser863) Polyclonal Antibody
Phospho-GluR1 (Ser863) 특이성을 가진 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합. 인간 GluR1 단백질의 Ser863 인산화 부위를 인식하며, 고순도(>95%) 및 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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Thermo Fisher Scientific Phospho-GluR1 (Ser863) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human GluR1 around the phosphorylation site of Serine 863 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.2) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553777 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of approximately 102 kDa.
Purity is greater than 95% by SDS-PAGE.
Target Information
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of L-glutamate induces a conformational change that opens the cation channel, converting the chemical signal into an electrical impulse. The receptor then rapidly desensitizes and enters a transient inactive state characterized by a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8, GluR1 shows resensitization characterized by delayed accumulation of current flux upon continued application of glutamate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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