Thermo Fisher Scientific TRPM8 Polyclonal Antibody
TRPM8 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합합니다. 합성 펩타이드 항원을 사용하여 제작되었으며, 냉감 수용체 연구에 활용됩니다. Lyophilized 형태로 제공되며 장기 보관 시 -20°C에서 안정적입니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human TRPM8 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: TRPM8.
Target Information
TRPM8 is a receptor-activated non-selective cation channel involved in the detection of sensations such as coolness, activated by temperatures below 25°C. It responds to icilin, eucalyptol, menthol, and changes in intracellular pH. TRPM8 is permeable to monovalent cations (Na⁺, K⁺, Cs⁺) and divalent Ca²⁺.
Expression is mostly restricted to prostate epithelial cells, with moderate levels in normal prostate tissue and elevated levels in prostate cancer. TRPM8 mRNA is also found in certain nonprostatic tumors (breast, colon, lung, skin), but rarely in corresponding normal tissues.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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