Thermo Fisher Scientific TRPV4 Polyclonal Antibody
TRPV4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB와 IHC에 사용 가능. 마우스 및 랫트 시료에서 검증됨. 합성 펩타이드 항원을 사용하여 제작. 동결건조 형태로 제공되며, 4°C 또는 -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1000–1:2000 | View 3 publications |
| Immunohistochemistry (IHC) | 1:1000–1:2000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 300–400 of mouse TRPV4 conjugated to a carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2209406 |
Product Specific Information
- Glycerol (1:1) may be added for additional stability.
- Reconstitute in 100 µL of sterile water.
- The peptide is homologous in rat and human.
Target Information
TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel activated in response to systemic osmotic pressure. It is a non-selective calcium-permeant cation channel involved in osmotic sensitivity and mechanosensitivity.
TRPV4 belongs to the OSM9-like transient receptor potential channel (OTRPC) subfamily within the TRP superfamily of ion channels.
Mutations in the TRPV4 gene are associated with spondylometaphyseal and metatropic dysplasia, as well as hereditary motor and sensory neuropathy type IIC.
Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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