Thermo Fisher Scientific UGCG Polyclonal Antibody
Human UGCG 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P)에서 1:50–1:200 희석 범위로 사용 가능. Antigen affinity chromatography로 정제됨. PBS/glycerol buffer에 보관하며 연구용으로 적합.
- 카탈로그번호
- PA554986
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UGCG. Recombinant protein control fragment (Product # RP-93000) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649242 |
Product Specific Information
Immunogen sequence:
RLHLNKKATD KQPYSKLPGV SLLKPLKGVD PNLINNLETF FELDYPKYEV LLCVQDHDDP AIDVCKKLLG KYPNVDARLF IGGKKVGINP KINNLMPGYE VAKYDLI
- Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 98%
Target Information
UGCG (UDP-glucose ceramide glucosyltransferase)는 ceramide에 glucose를 전달하는 glucosyltransferase로, flippase 역할도 할 수 있습니다.
UDP-glucose + N-acylsphingosine → UDP + D-glucosyl-N-acylsphingosine 반응을 촉매하며, 이는 glycosphingolipid 합성의 첫 단계인 ceramide glycosylation 과정입니다.
Glucosylceramide synthase (GlcT)와 lactosylceramide synthase (GalT)는 척추동물의 주요 glycosphingolipid 합성에 관여하는 핵심 효소입니다.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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