Thermo Fisher Scientific KIF12 Polyclonal Antibody
Human KIF12 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(Paraffin)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 40% glycerol 용액에 보관. 세포 내 수송 및 세포 분열 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | — |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | — |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KIF12. Recombinant protein control fragment (Product #RP-92969). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2643080 |
Product Specific Information
Immunogen sequence:
SAQCLPETLS TLRYASRAQR VTTRPQAPKS PVAKQPQRLE TEMLQLQEEN RRLQFQLDQM DCKASGLSGA RVAWAQRNLY GML
Highest antigen sequence identity to the following orthologs:
- Mouse: 77%
- Rat: 78%
Target Information
KIF12 encodes a member of the kinesin superfamily of microtubule-associated molecular motors with functions related to the microtubule cytoskeleton. Members of this superfamily play important roles in intracellular transport and cell division. A similar protein in mouse functions in the beta cell antioxidant signaling cascade, acting as a scaffold for the transcription factor specificity protein 1 (Sp1). Mice that lack this gene exhibit beta cell oxidative stress resulting in hypoinsulinemic glucose intolerance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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