Thermo Fisher Scientific IFRD1 Polyclonal Antibody
Human IFRD1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 시약이며, 0.2 mg/mL 농도. 단백질 발현 및 분화 경로 연구에 적합.
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- PA554985
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Thermo Fisher Scientific IFRD1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IFRD1. Recombinant protein control fragment (Product #RP-92274). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642645 |
Product Specific Information
Immunogen sequence:
AKVDKRKQRS VFRDVLRAVE ERDFPTETIK FGPERMYIDC WVKKHTYDTF KEVLGSGMQY HLQSNEFLRN VFELGPPVML DAATLK
Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 95%
Target Information
Tis7, also known as IFRD1, is a 442 amino acid membrane-associated, non-nuclear intracellular protein belonging to the IFRD family. It regulates gene activity in proliferative and differentiative pathways induced by NGF. Tis7 may act as an autocrine factor modulating ligand-induced signaling and enhancing adaptive responses by stimulating enterocyte differentiation. It functions as a negative regulator of transcriptional activity, repressing genes involved in myogenesis, muscle maintenance, and regeneration through a histone deacetylase-dependent mechanism.
Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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