
Thermo Fisher Scientific C17orf37 Monoclonal Antibody (OTI3D9), TrueMAB
C17orf37 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화됨. 인간 시료에 반응하며, 동결건조 형태로 제공. 재구성 시 1 mg/mL 농도 권장. 유방암 관련 바이오마커 연구에 유용.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D9 |
| Immunogen | Full length human recombinant protein of human C17orf37 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The ERBB2 (neu/HER2) oncogene is a key predictor of patient outcomes and therapy response in breast cancer.
C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. The C35 gene is located on chromosome 17q12, approximately 505 nucleotides from the 3′ end of the ERBB2 oncogene, the antigenic target for trastuzumab (Herceptin) therapy.
The chromosomal arrangement of C35 and ERBB2 genes is tail-to-tail. The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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