Thermo Fisher Scientific C17orf37 Monoclonal Antibody (OTI2D2), TrueMAB
C17orf37 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC(P), Flow Cytometry에 적합합니다. Human, Mouse, Rat, Dog 반응성이 있으며, Lyophilized 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D2 |
| Immunogen | Full length human recombinant protein of human C17orf37 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The ERBB2 (neu/HER2) oncogene is a critical predictor for patient outcome and therapy response in breast cancer.
C35 (C17orf37) is a novel tumor biomarker highly expressed in breast cancer.
The C35 gene is located on chromosome 17q12, approximately 505 nucleotides from the 3′ end of the ERBB2 oncogene, the target for trastuzumab (Herceptin) therapy.
C35 and ERBB2 genes are arranged tail-to-tail. The ORF37 open reading frame encodes a 12-kDa protein of currently unknown function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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