Thermo Fisher Scientific C17orf37 Monoclonal Antibody (OTI3D2), TrueMAB
인간 C17orf37 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 유세포분석에 사용 가능. 고순도 친화 크로마토그래피 정제 제품이며, 동결건조 형태로 제공. 암 관련 바이오마커 연구 및 단백질 발현 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D2 |
| Immunogen | Full length human recombinant protein of human C17orf37 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
C17orf37 (C35) is a novel tumor biomarker highly expressed in breast cancer. It is located on chromosome 17q12, approximately 505 nucleotides downstream of the ERBB2 (neu/HER2) oncogene. The C35 gene and ERBB2 are arranged tail-to-tail. The ORF37 open reading frame encodes a 12-kDa protein of unknown function.
The ERBB2 oncogene is a well-established predictor of patient outcome and therapeutic response in breast cancer. Identification of shared tumor-specific targets like C35 aids in developing broadly applicable cancer therapies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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