Thermo Fisher Scientific C17orf37 Monoclonal Antibody (OTI2D4), TrueMAB
C17orf37 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot과 유세포분석에 적합. E.coli에서 생산된 full-length human recombinant protein을 면역원으로 사용. Lyophilized 형태로 제공되며, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D4 |
| Immunogen | Full length human recombinant protein of human C17orf37 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The ERBB2 (neu/HER2) oncogene is a key predictor of patient outcome and therapeutic response in breast cancer.
C35 (C17orf37) is a novel tumor biomarker highly expressed in breast cancer.
The C35 gene is located on chromosome 17q12, 505 nucleotides downstream from the ERBB2 oncogene, the antigenic target for trastuzumab (Herceptin) therapy.
These genes are arranged tail-to-tail, and the ORF 37 encodes a 12 kDa protein of unknown function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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