Thermo Fisher Scientific MMP14 Polyclonal Antibody
MMP14 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, Flow Cytometry 등 다양한 응용에 적합. 고순도 항원 친화 크로마토그래피 정제 및 2 mg/mL 농도 제공. 인간, 마우스, 랫트 반응성 확인.
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Thermo Fisher Scientific MMP14 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 2 publications |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25 | View publications |
| Immunocytochemistry (ICC/IF) | 1:100 | View publications |
| Flow Cytometry (Flow) | 1:10–1:50 | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 145–174 amino acids from the N-terminal region of human MMP14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2145180 |
Product Specific Information
This antibody is predicted to react with bovine, mouse, porcine, and rat based on sequence homology.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes like arthritis and metastasis.
Most MMPs are secreted as inactive proproteins that are activated when cleaved by extracellular proteinases.
The protein encoded by this gene belongs to the membrane-type MMP (MT-MMP) subfamily, containing a potential transmembrane domain suggesting expression at the cell surface.
This protein activates MMP2, which may contribute to tumor invasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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