Thermo Fisher Scientific EVI1 Recombinant Rabbit Monoclonal Antibody (11H41L13)
EVI1 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체. Western blot 및 Immunocytochemistry에 적합하며, 높은 특이성과 재현성을 제공. 인간 반응성, 단기 4°C 및 장기 -20°C 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 11H41L13 |
| Immunogen | Peptides corresponding to Human MECOM (aa 367–384, 901–918) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2633048 |
Product Specific Information
This antibody is predicted to react with Monkey, Rabbit, and Bat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
Target Information
EVI1 (MECOM) is a transcriptional regulator and oncoprotein involved in hematopoiesis, apoptosis, development, cell differentiation, and proliferation. It interacts with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9.
The EVI1 gene can undergo translocation with the AML1 gene, resulting in overexpression and the onset of leukemia. Several transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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