Thermo Fisher Scientific PAK6 Polyclonal Antibody
PAK6 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot과 Immunocytochemistry에 적합합니다. 인간 시료 반응성이 있으며, Rabbit IgG로 제작되었습니다. 액상 형태, 항원 친화 크로마토그래피로 정제되어 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–4 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 13 amino acid peptide from near the center of human PAK6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152904 |
Product Specific Information
A suggested positive control is Raji cell lysate.
PA5-20231 can be used with blocking peptide PEP-0367.
Target Information
PAK6 is a serine/threonine kinase expressed in the testis and prostate. It associates with both the estrogen and androgen receptors. The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac.
They are divided into two groups:
- Group 1 (PAK1, 2, 3): Activated by Cdc42/Rac binding and involved in gene transcription, apoptosis, and cell morphology/motility.
- Group 2 (PAK4, 5, 6): Not activated by Cdc42/Rac binding; activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting a role in stress-related cellular responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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