Thermo Fisher Scientific CD19 Monoclonal Antibody (6OMP31), Biotin, eBioscience
CD19 단백질을 인식하는 6OMP31 클론의 Rat 모노클로날 항체로 Biotin 결합형입니다. 인간, 마우스, 랫트 시료에 반응하며 IHC(F/P) 및 Western blot에 사용 가능합니다. B세포 발달 및 활성 연구에 적합하며 4°C 암소 보관이 권장됩니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Thermo Fisher Scientific CD19 Monoclonal Antibody (6OMP31), Biotin, eBioscience™
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | - | 7 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1 µg/mL | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1 µg/mL | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Recommended Isotype Control | Rat IgG2a kappa Isotype Control (eBR2a), Biotin, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6OMP31 |
| Conjugate | Biotin |
| Available Formats | Unconjugated, Alexa Fluor 488, Custom conjugation |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2637168 |
| Filtration | 0.2 µm post-manufacturing filtered |
Product Specific Information
The 6OMP31 monoclonal antibody reacts with human, mouse, and rat CD19. CD19 is a transmembrane glycoprotein belonging to the immunoglobulin superfamily, expressed by B cells throughout development except on plasma cells and follicular dendritic cells. It acts as a B cell co-receptor, forming complexes with CD21, CD81, Leu13, and MHC class II, and plays a key role in B cell activation and proliferation.
CD19 deficiency leads to impaired humoral immunity, while mutations are linked to immunodeficiency syndromes. CD19 is expressed on most B cell tumors, including acute lymphoblastic leukemia and B cell lymphomas. CD19 antibodies are under investigation for therapeutic use in lymphoma, leukemia, and autoimmune disorders.
Applications Reported: Western blotting, immunohistochemistry on frozen and paraffin-embedded sections.
Applications Tested: Effective at ≤1 µg/mL for IHC (P) and IHC (F) with appropriate antigen retrieval. Optimal titration recommended.
Target Information
CD19, a member of the immunoglobulin superfamily, has two Ig-like domains and is expressed on all peripheral B cells. It may also appear on myeloid leukemia cells. CD19 acts as a signal-amplifying co-receptor for the B cell receptor (BCR), regulating B cell proliferation and differentiation. Mutations cause hypogammaglobulinemia, while overexpression leads to B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific CD21/CD35 Monoclonal Antibody (eBio8D9 (8D9)), Biotin, eBioscience
288,400원
Thermo Fisher Scientific
Thermo Fisher Scientific CD19 Monoclonal Antibody (HIB19), Biotin, eBioscience
310,900원
Thermo Fisher Scientific
Thermo Fisher Scientific CD19 Monoclonal Antibody (6OMP31), Biotin, eBioscience
210,200원
Thermo Fisher Scientific
Thermo Fisher Scientific CD11b Monoclonal Antibody (C67F154), Biotin, eBioscience
1,257,100원
Thermo Fisher Scientific
Thermo Fisher Scientific CD19 Monoclonal Antibody (MB19-1), Biotin, eBioscience
273,700원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|