Thermo Fisher Scientific TBR1 Recombinant Rabbit Monoclonal Antibody (JF10-00)
TBR1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 IHC에 적합합니다. 높은 특이성과 재현성을 제공하며, 로트 간 일관성이 우수합니다. 단백질 A 정제, 액상 형태, 4°C 보관. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JF10-00 |
| Immunogen | Synthetic peptide within Human TBR1 (aa 30–75) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809841 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the rabbit immune repertoire
Target Information
The TBR1 gene belongs to a conserved family of genes sharing a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in developmental regulation.
In mice, disruption of a similar protein leads to loss of projection neurons in the olfactory bulbs and cortex, indicating its role in early cortical development. The C-terminal region is essential for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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