Thermo Fisher Scientific KCNJ1 (Kir1.1) Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Reconstitution: 25 µL, 50 µL 또는 0.2 mL의 이중 증류수(DDW)로 재용해합니다. 항체는 실온에서 동결건조 분말 형태로 배송되며, 도착 후 -20°C에 보관해야 합니다. 재용해된 용액은 4°C에서 최대 1주일 보관 가능하며, 장기 보관 시 소량으로 분주하여 -20°C에 보관하십시오. 반복적인 동결 및 해동은 피하십시오. 사용 전 모든 항체 용액은 10,000 × g에서 5분간 원심분리하십시오.

Target Information

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiological responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and likely plays an important role in potassium homeostasis. The encoded protein preferentially allows potassium to flow into a cell rather than out. Mutations in this gene are associated with antenatal Bartter syndrome, characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.