Thermo Fisher Scientific Ovomucoid Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Positive control: Ovomucoid

Target Information

Ovomucoid is isolated from chicken egg white. The precursor is a 210 amino acid secreted protein consisting of three homologous, tandem Kazal family inhibitory domains, each homologous to pancreatic secretory trypsin inhibitor (Kazal) and each with a reactive site for inhibition of serine proteinases.
The major reactive site for bovine beta-trypsin is the Arg89–Ala peptide bond in the second domain. Ovomucoid causes allergic reactions in humans and is a major allergen in chicken egg.
Egg protein allergies are common in infants and young children, with both IgG and IgA antibodies detectable. Ovalbumin intolerance has been associated with several pediatric conditions, including cystic fibrosis and certain kidney diseases.
A possible relationship between food allergy and infantile autism has been observed. Children with insulin-dependent diabetes mellitus show enhanced immune responses to both β-lactoglobulin and ovalbumin, which may relate to disease development.
Conditions related to ovalbumin intolerance usually resolve once egg-based foods are removed from the diet. Intolerance may be due to multiple egg proteins, including those in yolk.
Major chicken egg proteins include:

• Ovalbumin (45 kDa, 54%)
• Conalbumin (80 kDa, 13%)
• Ovomucoid (28 kDa, 11%)
• Lysozyme (14 kDa, 3.5%)
• Other minor proteins

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 없음)