Thermo Fisher Scientific ZBTB17 Monoclonal Antibody (OTI4F3), TrueMAB
ZBTB17 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 최적화됨. 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 세포주기 조절 및 림프구 발달 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 112–457 of human ZBTB17 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ZBTB17 is a transcription factor that can act as an activator or repressor depending on its binding partners. It targets negative regulators of cell cycle progression and plays a crucial role in early lymphocyte development by preventing apoptosis in lymphoid precursors. It enables survival in response to IL7 and supports proper lineage commitment.
ZBTB17 binds promoters of adenovirus major late protein and cyclin D1 to activate transcription and is required for early embryonic development during gastrulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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