Thermo Fisher Scientific Ataxin 7 Monoclonal Antibody (3SCA-1C1)
인간 및 마우스 Ataxin 7 단백질을 인식하는 단클론 항체. Western blot, ICC/IF, ELISA에 적합. 비결합형 액상 형태로 제공되며, -20°C에서 보관. 신경퇴행성 질환 연구용으로 적합.
- 카탈로그번호
- MA3083
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3SCA-1C1 |
| Immunogen | Recombinant human Ataxin 7 aa 1–229 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2633328 |
Product Specific Information
- MA3-083 detects Ataxin 7 from human and mouse samples.
- Successfully used in Western blot, immunofluorescence, and ELISA applications.
- The epitope is mapped between amino acids 66 and 119.
Target Information
Spinocerebellar ataxia type 7 (SCA7) is a hereditary neurodegenerative disease characterized by expanded polyglutamine (CAG) repeats at the N-terminus.
This autosomal dominant cerebellar ataxia affects the cerebellum, retina, and brain stem, leading to dementia and macular degeneration.
The SCA7 gene encodes the 892-residue protein ataxin-7, typically located in the cytoplasm and on the nuclear membrane of normal brain neurons.
Mutations in SCA7 cause ataxin-7 accumulation in intranuclear inclusions, which can result in neuronal cell death.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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