Thermo Fisher Scientific ATXN7L3 Monoclonal Antibody (2ATX-2B1)
ATXN7L3 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody입니다. Western blot과 Immunofluorescence에 적합하며, Human과 Mouse 시료에서 반응합니다. SAGA 복합체 연구 및 전사 조절 관련 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2ATX-2B1 |
| Immunogen | Synthetic Peptide coupled to Ovalbumin corresponding to aa 278–296 of human ATXN7L3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.05% Sodium Azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet Ice |
| RRID | AB_2633329 |
Product Specific Information
MA3-084 detects Ataxin 7L3 from human and mouse samples.
MA3-084 has been successfully used in Western blot, immunofluorescence, and ELISA applications.
Target Information
Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination.
Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B.
The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription.
Required for nuclear receptor-mediated transactivation.
Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Regulates H2B monoubiquitination (H2Bub1) levels and affects subcellular distribution of ENY2, USP22, and ATXN7L3B.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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