Thermo Fisher Scientific AID Monoclonal Antibody (1AID-2E11)
AID 단백질을 검출하는 Mouse monoclonal 항체로, Western blot, ICC/IF, Flow cytometry 등에 사용 가능. Human 및 Mouse 시료에 반응하며, 비결합(Unconjugated) 형태의 액상 제품. -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:500 | - |
| Flow Cytometry (Flow) | 1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1AID-2E11 |
| Immunogen | Synthetic peptide coupled to Ovalbumin corresponding to aa 185–198 of mouse AID |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.05% Sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2633326 |
Product Specific Information
- MA3-081 detects AID from human and mouse samples.
- Validated for Western blot, immunofluorescence, flow cytometry, and ELISA applications.
- Immunogen: synthetic peptide coupled to ovalbumin (aa 185–198).
- Detects Isoform 1 (~24 kDa) and Isoform 2 (~22 kDa) in human samples.
Target Information
This gene encodes an RNA-editing deaminase belonging to the cytidine deaminase family.
It is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes.
Defects in this gene cause autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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