Thermo Fisher Scientific GPX4 Recombinant Rabbit Monoclonal Antibody (JU11-31)
Thermo Fisher의 GPX4 Recombinant Rabbit Monoclonal Antibody (JU11-31)는 인간, 마우스, 랫, 제브라피쉬에 반응하며 WB, IHC, ICC에 적합합니다. 재조합 단클론 항체로 높은 특이성과 일관성을 제공하며, 단기 4°C, 장기 -20°C 보관이 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:10,000 | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat, Zebrafish |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JU11-31 |
| Immunogen | Synthetic peptide within Human GPX4 aa 23–72 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% Sodium Azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2810103 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione, protecting cells against oxidative damage. Human plasma glutathione peroxidase is a selenium-containing enzyme, where the UGA codon translates into selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and cleavage sites of mitochondrial and nuclear transit peptides need to be experimentally verified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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