Thermo Fisher Scientific alpha-II Spectrin Recombinant Rabbit Monoclonal Antibody (JU32-09)
Recombinant rabbit monoclonal antibody recognizing alpha-II spectrin (SPTAN1). Validated for WB and IHC (P). Offers high specificity, lot-to-lot consistency, and animal origin-free formulation. Suitable for human, mouse, and rat samples. For research u...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JU32-09 |
| Immunogen | Synthetic peptide within Human Alpha Fodrin (aa 46–95) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2810102 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Key advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the rabbit immune repertoire
Target Information
SPTAN1 (Spectrin alpha chain, non-erythrocytic 1) is a member of the spectrin family of filamentous cytoskeletal proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins form tetramers composed of alpha and beta dimers linked in a head-to-head arrangement.
SPTAN1 also plays roles in DNA repair and cell cycle regulation. Mutations in this gene are associated with early infantile epileptic encephalopathy-5. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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