Thermo Fisher Scientific Artemin Polyclonal Antibody
Thermo Fisher Scientific의 Artemin Polyclonal Antibody는 인간 Artemin 단백질에 특이적인 염소 유래 IgG 항체로, WB 및 IHC에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 신경영양 인자 연구 및 GDNF 계열 단백질 분석에 활용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (IHC) | 5–15 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human Artemin Ala108–Gly220 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607473 |
Product Specific Information
- In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse Artemin is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of the antibody (LAL method).
Target Information
The protein encoded by this gene is a member of the glial cell line-derived neurotrophic factor (GDNF) family of ligands, which belong to the TGF-beta superfamily of signaling molecules.
GDNFs possess neurotrophic properties and have potential applications in gene therapy for neurodegenerative diseases.
Artemin supports the survival of several peripheral neuron populations and at least one dopaminergic CNS neuron population.
Its expression pattern near these neurons supports its role in both PNS and CNS.
Artemin acts as a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor.
Multiple transcript variants encoding different isoforms of this gene have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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