Thermo Fisher Scientific TGFBI Polyclonal Antibody
TGFBI 단백질을 인식하는 Thermo Fisher Scientific의 sheep polyclonal 항체. Western blot, IHC(F), ELISA에 사용 가능. 높은 특이성과 낮은 교차반응성을 보이며, 동결건조 형태로 제공되어 안정적 보관 가능. 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
| ELISA | 0.1–0.4 µg/mL (Detection), 0.2–0.8 µg/mL (Capture) |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse beta IG-H3 (Gly24–His683) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608243 |
Product Specific Information
In sandwich ELISAs, less than 6% cross-reactivity with recombinant human (rh) beta IG-H3 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene encodes an RGD-containing protein that binds to type I, II, and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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