Thermo Fisher Scientific LILRA3 Polyclonal Antibody
인간 LILRA3 단백질을 인식하는 염소 유래 다클론 항체로, Flow Cytometry 및 ELISA에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공됩니다. PBS(5% 트레할로스) 완충액에 보관하며, -20°C에서 보관 권장.
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Applications
- Flow Cytometry (Flow): 0.25 µg per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human LILRA3/CD85e (Arg18–Glu439) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606668 |
Product Specific Information
- In direct ELISAs, approximately 30% cross-reactivity with recombinant human ILT2, ILT4, ILT5 is observed.
- Less than 5% cross-reactivity with rhLIR5 and rhLIR7.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer (NK) cells.
All LIRs in subfamily B have an inhibitory function (e.g., LILRB1, MIM 604811).
LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (e.g., LILRA1, MIM 604810).
One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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