Thermo Fisher Scientific Cytokeratin 14 Monoclonal Antibody (RCK107)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:1,000

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:200

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Flow Cytometry (Flow)

1:100-1:200

-

Product Specifications

Species Reactivity

Dog, Human, Pig, Rat

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

RCK107

Immunogen

Cytoskeletal preparation of TR146 epithelial cells. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cytokeratin 14,uniProtId:P02533-1,ncbiNodeId:9606,antigenRange:1-472,antigenLength:472,antigenImageFileName:MA1-06323_Cytokeratin_14_P02533-1_House_mouse.svg,antigenImageFileNamePDP:MA1-06323_Cytokeratin_14_P02533-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

purified

Storage buffer

PBS

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2134823

Product Specific Information

MA1-06323 detects cytokeratin 14 in human, rat, canine, and porcine samples.

MA1-06323 has sucessfully been used in Western blotting, immunocytochemistry and immunohistochemistry.

The MA1-06323 immunogen is a cytoskeletal preparation of TR146 epithelial cells.

Store at 4ºC or in small aliquots at -20ºC.

Target Information

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.