Thermo Fisher Scientific ICAM-3 Monoclonal Antibody (ICAM3.1)
인간 ICAM-3 단백질을 인식하는 Mouse IgG1 단클론 항체로 다양한 면역분석(WB, IHC, Flow, ELISA 등)에 사용 가능. 단백질 A로 정제된 액상 형태이며, PBS 용액에 보존제 없이 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | Assay-dependent | |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | |
| Flow Cytometry (Flow) | Assay-dependent | |
| ELISA | Assay-dependent | |
| Immunoprecipitation (IP) | Assay-dependent | |
| Radioimmune Assays (RIA) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ICAM3.1 |
| Immunogen | ICAM 3Fc chimeric fusion protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2122323 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, serving as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin.
ICAM-3 mediates the contact between T cells and antigen-presenting cells, regulates LFA-1 affinity for ICAM-1, and induces T cell activation and proliferation.
It plays an essential role in initiating immune responses on T cells and antigen-presenting cells, and interacts with CD209 (DC-SIGN), a C-type lectin of dendritic cells and macrophages, facilitating communication between dendritic cells and granulocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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