Thermo Fisher Scientific PHGDH Monoclonal Antibody (OTI9C2), TrueMAB

Applications

• Western Blot (WB): 1:500
• Immunohistochemistry (Paraffin) (IHC (P)): 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

The PHGDH gene encodes an enzyme involved in the early steps of L-serine synthesis in animal cells.
L-serine is essential for D-serine and other amino acid synthesis.
The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity.
Mutations in this gene have been associated with congenital microcephaly, psychomotor retardation, and other symptoms.
Multiple alternatively spliced transcript variants exist, but most full-length forms are not yet characterized.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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