Thermo Fisher Scientific FLT4 Monoclonal Antibody (OTI9G6), TrueMAB
인간 FLT4(VEGFR3)에 특이적인 마우스 단일클론 항체로 Western blot에 적합. 동결건조 형태이며 1 mg/mL 농도. 혈관 및 림프관 형성 연구용으로 사용. 연구용으로만 제공, 진단용 불가.
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- CF806910
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Thermo Fisher Scientific FLT4 Monoclonal Antibody (OTI9G6), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9G6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1063–1363 of human FLT4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Vascular endothelial growth factor (VEGF) is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues.
Unlike VEGF, VEGFC stimulates lymphatic vessel growth through its specific lymphatic endothelial receptor VEGFR-3.
Inactivation of the VEGFR-3 gene in mice causes defective blood vessel development in early embryos, resulting in abnormal vessel organization and cardiovascular failure at embryonic day 9.5.
Thus, VEGFR3 plays an essential role in embryonic cardiovascular development before lymphatic vessel formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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