Thermo Fisher Scientific MMP3 Monoclonal Antibody (OTI3C6), TrueMAB
인간 MMP3 단백질(aa 246-477)에 특이적인 마우스 단클론 항체. Western blot에서 검증됨. 동결건조 형태로 제공되며, PBS(pH 7.3)와 8% 트레할로오스 함유. 연구용으로 조직 재생 및 단백질 분해 관련 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 246–477 of human MMP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted as a pro-protein and activated by extracellular proteinase cleavage.
MMP3 binds zinc and calcium ions, exhibiting metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin, playing a role in wound repair and tissue remodeling.
Mutations in MMP3 can be associated with coronary heart disease 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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