Thermo Fisher Scientific CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) Monoclonal Antibody (BCMA/7254)
인간 CD269/BCMA 단백질을 인식하는 Mouse IgG2 monoclonal antibody. Western blot 및 IHC(paraffin) 적용 가능. Protein A/G 정제, PBS+BSA buffer로 제공. B세포 성숙 및 생존 관련 연구용.
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Applications
Western Blot (WB)
- Tested Dilution: 2–4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BCMA/7254 |
| Immunogen | Recombinant human CD269 protein fragment (aa 1–184) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: NAMALWA or Daudi cells; tonsil or gastric carcinoma (IHC)
- Cellular Location: Cell surface
Target Information
The protein encoded by this gene is a member of the TNF-receptor superfamily. It is preferentially expressed in mature B lymphocytes and may play a role in B cell development and autoimmune response. This receptor binds to TNFSF13B/TALL-1/BAFF, leading to NF-kappaB and MAPK8/JNK activation. It also interacts with TRAF family members to transduce signals for cell survival and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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