Thermo Fisher Scientific CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) Monoclonal Antibody (rCD269/8507)
인간 CD269/BCMA 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, IHC 및 ELISA 등 다양한 연구용 응용에 적합. 고순도 Protein A/G 정제, PBS 버퍼에 보존제 무첨가. B세포 성숙 및 생존 신호 연구에 활용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rCD269/8507 |
| Immunogen | Recombinant human CD269 protein fragment (around aa 1–184) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the TNF-receptor superfamily.
This receptor is preferentially expressed in mature B lymphocytes and may play an important role in B cell development and autoimmune response.
It specifically binds to TNFSF13B (TALL-1/BAFF), leading to NF-kappaB and MAPK8/JNK activation.
Additionally, it interacts with TRAF family members, transducing signals for cell survival and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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