Activotec Activo-P11 Automated Peptide Synthesizer

The Activo-P11 Peptide Synthesizer is an easy to use and affordable instrument for synthesis of very high quality peptides.

Description

The Activo-P11 is the only synthesizer available with both automated reactor heating and UV monitoring. These valuable synthesis tools allow chemists to synthesize longer and more difficult peptides and to gain more synthesis information about those peptides. For example the antimicrobial peptide Gomesin has been successfully synthesized using conventional heating.

The most reliable and lowest running cost synthesizer available. Compatible with green chemistry solvents.

New Automated Peptide Synthesis with UV Monitoring
New ActivoPep Software Release for the P11 Peptide Synthesizer – click here for details
Activo-P11 Brochure download
Activo-P11 UV Monitoring Brochure download

Key Features

• High quality peptides
• Any scale from 0.005 to 5.0 mmol
• Easy to use; define own protocols or use the peptide wizard software
• Performs any Fmoc or t-Boc chemistries
• Compatible with green chemistry protocols and reagents
• PNA synthesis
• Safe to use, instrument is totally enclosed
• Fully automatic with no limit to number of amino acids
• Disposable reactors and amino acid containers
• Uses commercially available amino acids, resins and reagents
• Self diagnostics with fluidic sensors checking reagent delivery, emptying and transfers

High Quality Peptide

• Inert atmosphere throughout
• Precise and fast reagent delivery and washing
• Efficient inversion mixing
• Bottom filtration from disposable reactors
• Fresh amino acids in powder
• Pre-activation vessel
• Multi-tasking
• Heated reactors
• UV monitoring

Chemistry

• Fmoc or t-Boc
• PNA synthesis
• In situ or preactivation
• Use any coupling reagents; HBTU, HCTU, HATU, TBTU, PyBOP, DIC etc
• Green chemistry compatible hardware and software
• Use any resins; polystyrene or PEG based supports
• Use any protocols
• Synthesize any length of peptides

Ease of Use

• Very easy to use software; import the sequence, fill in quantity and resin specifications then press run
• Software generated worksheet tells the user what to prepare
• Free choice of chemistry, present and future
• Disposable reactors and amino acid containers
• 60 amino acid containers, no limit to how many can be added
• Enclosed cabinet for safe bench top use
• Logfile of each synthesis
• Easy cleavage on the machine or transfer disposable reactor to the Activo-P12 Cleavage Device

Technical Support

Activotec has been supplying quality custom peptides for many years, we have unsurpassed experience in the synthesis and automation processes. The Activo-P11 is used in both our peptide production and our peptide research facilities. Activotec is totally committed to supporting its customers worldwide.

• Fast reliable service engineers and application chemists.
• Service contract options are available to suit your requirements.
• Peptide chemists are available to help with instrument application and peptide chemistry if required.
• Training is provided on site or in our facility.

Dimensions

W – 84cm or 33in D – 59cm or 23in H – 70cm or 28in

Instrument Specification

Scale	0.005 to 5.0 mmol
Chemistry	Fmoc or t-Boc Dissolve dry amino acids or use pre dissolved
Activation method	Pre-activation or in situ, user selectable. HBTU, HCTU, COMU, DIC, PyBop etc
Amino acid vessels	60 of 15 mL or 30 of 50 mL arranged in a carousel so no limit
Reaction vessel sizes	10 mL, 40 mL and 125 mL
Reagent/solvent bottles	9, range from 250 mL to 19 litres 2 of 10 litres each
Mixing system	Over centre mixing with variable speed and amplitude
Inert atmosphere	100% throughout the system
Fluid measurement	Fill loops for calibration free measurement of reagents Timed delivery for washing solvents
Power	Variable range from 240V/50 Hz to 100V/ 60 Hz
Safety	CE marked, system enclosed with door interlock
Ventilation	Designed for bench top use with extractor attached
Logfile	Printable logfile for each synthesis run
Software	User friendly interface, pre-written protocols or user defines own
Controller	Desktop PC
Temperature	Ambient to +90 ºC
Dimensions	Width 84 cm (33″), depth 60 cm (23″), height 70 cm (28″)