Thermo Fisher Scientific AKAP5 Polyclonal Antibody
Rabbit polyclonal antibody targeting AKAP5 (AKAP150) for research use in Western blot applications. Lyophilized form, reconstituted with deionized water. Unconjugated, stored at -20°C. Specific to neuronal AKAP5 involved in PKA localization and signaling.
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Applications
- Western Blot (WB): Tested dilution 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)RGAKRSRPSKLTED, corresponding to amino acid residues 128–141 of rat AKAP150 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735440 |
Product Specific Information
- Product is shipped at room temperature as a lyophilized powder.
- Store at -20°C upon receipt.
- Reconstitution: Add 50 µL of deionized water.
Target Information
A-kinase anchoring proteins (AKAPs) are scaffolding proteins that bind regulatory subunits of Protein Kinase A (PKA), localizing PKA activity to distinct cellular regions.
AKAP5 (also known as P75, AKAP75, or AKAP79) is mainly expressed in neuronal tissues, where it anchors type II PKA to post-synaptic densities and plasma membrane junctions.
It interacts with calmodulin, PP2B, and calcineurin, coordinating cAMP- and Ca²⁺-sensing pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-77705_AKAP5_P24587-1_Rabbit.svg, PA5-77705_AKAP5_P24587-1_Rabbit_PDP.jpeg)
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