Thermo Fisher Scientific G6PD Polyclonal Antibody
Thermo Fisher Scientific의 G6PD Polyclonal Antibody는 인간 G6PD 단백질을 인식하는 rabbit polyclonal 항체로, WB, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 안정한 PBS/glycerol buffer에 보관됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human G6PD. Recombinant protein control fragment (Product # RP-91906) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789023 |
Product Specific Information
Immunogen sequence:
EVRLQFHDVA GDIFHQQCKR NELVIRVQPN EAVYTKMMTK KPGMFFNPEE SELDLTYGNR YKNVKLPDAY ERLILDVFCG SQMHFVRSDE LREAWRIFTP LLHQIELEKP
Target Information
This gene encodes glucose-6-phosphate dehydrogenase (G6PD), a cytosolic enzyme encoded by a housekeeping X-linked gene. Its main function is to produce NADPH, a key electron donor in defense against oxidizing agents and in reductive biosynthetic reactions.
G6PD shows high genetic diversity, with many variants resulting from missense mutations that affect enzyme activity and clinical presentation.
Deficiency in G6PD can lead to neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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