Thermo Fisher Scientific GAB2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GAB2. Recombinant protein control fragment (Product #RP-93668). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GAB2,uniProtId:Q9UQC2-1,ncbiNodeId:9606,antigenRange:145-265,antigenLength:676,antigenImageFileName:PA5-81866_GAB2_Q9UQC2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-81866_GAB2_Q9UQC2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789027

Product Specific Information

Immunogen sequence: LSSSSQHLLR ERKSSAPSHS SQPTLFTFEP PVSNHMQPTL STSAPQEYLY LHQCISRRAE NARSASFSQG TRASFLMRSD TAVQKLAQGN GHCVNGISGQ VHGFYSLPKP SRHNTEFRDS T

Target Information

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.