Thermo Fisher Scientific Human RIM2 Synthetic Peptide
인간 RIM2 단백질의 C-말단 16개 아미노산 서열에 해당하는 합성 펩타이드. 항체 차단 실험용으로 사용 가능하며, PA5-34557 항체와 함께 Western blot에서 활용. 정제된 액상 형태로, PBS 버퍼에 0.1% BSA와 0.02% sodium azide 포함. -20°C에서 보관.
- 카탈로그번호
- PEP1600
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human RIM2.
PEP-1600 can be used as a blocking peptide with polyclonal antibody PA5-34557.
For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
Target Information
Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain.
While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality due to defects in neurotransmitter release.
Synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca²⁺ triggers.
Like Rim1, Rim2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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