Thermo Fisher Scientific Human TLX3 Synthetic Peptide
인간 TLX3 단백질의 아미노 말단 부위에 해당하는 합성 펩타이드로, PA5-34555 항체의 블로킹용으로 사용 가능. 정제된 액상 형태이며 PBS 버퍼에 0.1% BSA 포함. 연구용으로만 사용되며 T-ALL 관련 TLX3 연구에 적합.
- 카탈로그번호
- PEP1598
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human TLX3 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to a 16 amino acid sequence near the amino terminus of human TLX3.
PEP-1598 can be used as a blocking peptide with polyclonal antibody PA5-34555.
For use as a blocking peptide in Western blot, incubate the peptide with an equal volume of antibody for 30 minutes at 37ºC.
Target Information
The Hox proteins play a role in embryonic development and cellular differentiation by regulating downstream target genes.
TLX3 (homeobox11-like1, HOX11L2) is a DNA-binding nuclear transcription factor expressed in a subset of the primary sensory nervous system.
TLX3, together with TLX1, promotes an excitatory glutamatergic neuronal phenotype over an inhibitory GABAergic phenotype, opposing LBX1 signals during dorsal spinal cord development.
Chromosomal translocations of the TLX3 gene have been associated with certain forms of T-cell acute lymphoblastic leukemia (T-ALL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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