Thermo Fisher Scientific CNTF Monoclonal Antibody (34738)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

ELISA (ELISA)

0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture)

-

Neutralization (Neu)

1-3 µg/mL

-

Product Specifications

Species Reactivity

Rat

Published species

Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

34738

Immunogen

E. coli-derived recombinant rat CNTF Ala2-Met200 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CNTF,uniProtId:P20294-1,ncbiNodeId:10114,antigenRange:2-200,antigenLength:200,antigenImageFileName:MA5-23730_CNTF_P20294-1_House_mouse.svg,antigenImageFileNamePDP:MA5-23730_CNTF_P20294-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2609246

Product Specific Information

In sandwich ELISAs, less than 3% cross-reactivity with recombinant human CNTF is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

Endoxin level is <1.0 EU per 1 µg of the antibody by the LAL method.

Target Information

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.