Thermo Fisher Scientific MCP-2 Monoclonal Antibody (35509)

Applications and Tested Dilution

ELISA (ELISA)

• Detection: 0.1–0.4 µg/mL
• Capture: 2–8 µg/mL

Neutralization (Neu)

• 1–4 µg/mL

Product Specifications

Product Specific Information

• In ELISAs, this antibody shows less than 0.1% cross-reactivity with recombinant human (rh) CCL15 and rmCCL3.
• Reconstitute at 0.5 mg/mL in sterile PBS.
• Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine belongs to the CC subfamily, characterized by two adjacent cysteine residues. It exhibits chemotactic activity for monocytes, lymphocytes, basophils, and eosinophils. By recruiting leukocytes to sites of inflammation, this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.