Thermo Fisher Scientific PGAM5 Recombinant Rabbit Monoclonal Antibody (7J3A5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:20,000-1:80,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500

-

Immunocytochemistry (ICC/IF)

1:300-1:1,200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

7J3A5

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-146 of human PGAM5 (NP_001164014.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PGAM5,uniProtId:Q96HS1-1,ncbiNodeId:9606,antigenRange:50-146,antigenLength:289,antigenImageFileName:MA5-51246_PGAM5_Q96HS1-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51246_PGAM5_Q96HS1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3094142

Product Specific Information

Immunogen sequence: GARPGPGVWD PNWDRREPLS LINVRKRNVE SGEEELASKL DHYKAKATRH IFLIRHSQYH VDGSLEKDRT LTPLGREQAE LTGLRLASLG LKFNKIV

Target Information

Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.